产品货号:
Z19323
中文名称:
KPNA2抗体
英文名称:
Anti-KPNA2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-KPNA2 Antibody |
指标别名 | Importin subunit alpha 2;IPOA1;Karyopherin subunit alpha 2;KPNA2;QIP2;RAG cohort protein 1;RCH1;SRP1;SRP1 alpha;SRP1alpha |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | KPNA2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | KPNA2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA2.The immunogen is located within amino acids 40 - 90 of KPNA2. |
计算分子量 | 58kDa |
成分 | KPNA2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | KPNA2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Karyopherin,a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits,is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring,Ran-dependent mechanism.The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm,while the beta subunit accumulates at the NPC.KPNA2 is the alpha subunit 2 of karyopherin,which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus.It is ubiquitously expressed and contains an IBB/importin beta domain,ten Armadillo repeats that bind "cargo" and three intervening nuclear localization sequences (NLSs).It has recently been reported to play an important role in tumorigenesis and tumor progression. |
Uniprot ID | P52292 |
基因名全称 | Karyopherin alpha 2 (RAG cohort 1,importin alpha 1) |
蛋白名全称 | Karyopherin alpha 2 (RAG cohort 1,importin alpha 1) |
推荐稀释比 | KPNA2 antibody can be used for detection of KPNA2 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human and rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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